Evidence that ultraviolet-induced thymine dimers in DNA cause biological damage.
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چکیده
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منابع مشابه
Serologic estimation of thymine dimers in the deoxyribonucleic acid of bacterial and mammalian cells following irradiation with ultraviolet light and postirradiation repair.
The repair of thymine dimers induced by irradiation with ultraviolet light was detected in the DNA of human fibroblast cells, HeLa, but not in the DNA of rat glial or rat pituitary cells. Thymine dimers were detected in the DNA of bacterial and mammalian cells after irradiation with levels of light which are biologically significant, as little as 50 ergs per mmz. The detection of thymine dimers...
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عنوان ژورنال:
- Proceedings of the National Academy of Sciences of the United States of America
دوره 48 شماره
صفحات -
تاریخ انتشار 1962